LDR brachytherapy: Studies

There is a wealth of information on the internet about prostate cancer and possible treatments for the disease. So much so that making a decision on the right treatment can seem an impossible task. BXTAccelyon are providers of products and services to clinics administering LDR brachytherapy across the UK, Ireland, New Zealand and Australia. LDR brachytherapy is a form of radiation therapy, and is of course just one possible treatment for prostate cancer, but one that we believe in and one that is proven to be successful.

 

There have been two major studies on the effectiveness of LDR brachytherapy as a treatment for prostate cancer in recent years. Find out more about them here:

 

 

PCRSG Study

 

The study compared the outcomes from treatments involving robotic radical prostatectomy (surgical removal of the prostate), radical prostatectomy, proton therapy, cryotherapy, External Beam Radiation Therapy (EBRT), and brachytherapy.

 

 

Using readings of Prostate Specific Antigen (PSA) a protein released by the prostate into the blood to measure cancer-free progression, the study found low dose rate brachytherapy was superior to other treatments in low-risk disease, including surgical removal of the prostate). The superiority was maintained for intermediate-risk cases, while for high-risk cases seed brachytherapy was the most effective if combined with EBRT

 

 

 

 

 

 

ASCENDE RT Study

 

The ASCENDE-RT (Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy) study was the first randomized clinical trial comparing brachytherapy to the traditional use of external beam radiation therapy to treat intermediate and high risk Prostate Cancer patients over a period of between 6 to 9 years.

 

The results show a significant increase in survival rates with an average of 50% of patients showing progression free survival when treated with LDR brachytherapy.

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